1.
Biomarkers
; 17(2): 134-9, 2012 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22188331
RESUMO
CONTEXT: Neopterin serum concentration increases in the presence of renal dysfunction. OBJECTIVE: We sought to determine the relationship between admission serum neopterin levels and worsening renal function (WRF) in patients with heart failure (HF). METHODS: We prospectively measured serum neopterin levels in patients with HF and the patients were subdivided into two groups: with and without WRF during hospital admission. RESULTS: Logistic regression analysis showed that high serum neopterin levels at admission were associated with a greater likelihood of developing WRF. CONCLUSIONS: Patients admitted to hospital with HF, elevated serum neopterin levels are associated with an increased risk of developing WRF.